CDPC Colentina Project co-financed by the European Fund of Regional Development. ...............








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          The R&D project aims at developing the necessary infrastructure with a view to increasing the efficiency of research-development activities by creating the “Research-Development Pavilion” within the Colentina Hospital in Bucharest.

          The building was raised during 1936 - 1938 in order to host the Internal Medicine Clinic, leaded by the famous Prof. N. Gh. Lupu. The structure consisted in separate clinic units  with beds and laboratories (1-3 of surface). Since then, the  initial destination hasn’t been changed, during all this time, the Internal Medicine Clinics of Colentina Hospital carried on their activities, in this pavillion. But, starting with the externalization of medical laboratory services and with the decrease in the number of hospital beds the pavillion was, in time, disabled and mentained in conservation.

          The existing building D+P+3+M, within the Colentina Clinical Hospital, functioned as a medical pavilion, in state of preservation. The building’s structure is made of reinforced concrete frames with reinforced concrete slabs, roofing is of timber support and covered with zinc-plated sheets.

General objective:
          Integrating the research-development-innovation activity of the health thematic area into the innovative, knowledge-based economic activity emergent in the Bucharest – Ilfov Development Region as well as in the European research area (ERA).

Specific objective:
Establishment of a Research Pavilion:
1. creating a modern research infrastructure for medical-surgical research (specialties: allergology, internal medicine, neurology, dermatology, surgery, orthopedics and pathological anatomy) within the Colentina Hospital in Bucharest;
2. modernization of the necessary location and the endowment thereof with state-of-the-art researchdevelopment equipment for the performance of major scientific and technological projects related to the Heath thematic area, in partnership with research teams within national institutes, universities and the private sector.

Through the accomplishment of these objectives, Colentina Hospital in Bucharest will be able:
1. to develop the fundamental and applicative research infrastructure in the medical-surgical field (specialties: allergology, internal medicine, neurology, dermatology, surgery, orthophedics and pathologic anatomy) as well as the related material base, which will enable the performance pf elaborated researches and reduce the existing gap between our country and the EU;
2. to ensure medical research activities in “top” fields which would enable the access to national and international programmes in the medical field as well as the practical application of medical research outputs;
3. to approach new subfields of the immunoinflammatory pathology of the respiratory tracks, tegument and central nervous system:

  • Research in the etiopathologic field of environment allergens (pollens, moulds, mites);
  • Research in hepatic inflammatory pathology (etiologic agents identification, pro and anti fibrogenetic factors establishment, prognosis factors and therapeutic lines);
  • Research in the cutaneous aging field by studying the physical properties of the tegument;
  • Research in the cutaneous epithelisation field by identifying structural anatomic factor contributing to the regeneration of keratinocytes;
  • Research in the pharmacokinetics of dermatologic topics through the ultra structural study on increasing modern therapeutic methods efficiency for the treatment of vascular component cutaneous diseases;
  • Research in the etiopathogenesis of neuromuscular diseases by identifying the chemical activity at the level of affected tissues;
  • Research in cerebral metabolism and pathological mechanisms involved in the vascular and degenerative cerebral pathology.

4. to diversify the educational performance by supplying annual professional training programmes for over 1800 students/MA students /PhD students;
5. to establish a centre of excellence in the fields of allergology, neurology, dermatology, orthopedics and pathologic anatomy, highly known at European and global level but little explored in Romania;
6. to extend research and education thematic areas and the interdisciplinary cooperation between our institute and other EU and local centers;
7. to optimally develop the scientific potential of medical-surgical researchers: internal medicine, neurology, dermatology, orthophedics and pathologic anatomy by taking part in European R&D programmes and increasing the number of ISI/Medline indexed articles in order to reduce the gap between fundamental research in Romania and in the EU;
8. to efficiently develop human and material resources in the following medical-surgical specialties: allergology, internal medicine, neurology, dermatology, orthophedics and pathologic anatomy in order to ensure the necessary scientific competence for national and international recognition and certification;
9. to attract young researchers and to train them in high performance scientific fields; to attract high expertise specialists;
10. to create a team for training specialists in centre’s fields;
11. to improve the quality of life for patients suffering from neurological degenerative diseases, allergological respiratory diseases, conjunctive tissue diseases (collagen illnesses) cutaneous vascular diseases by bringing the diagnosis algorithm into line with the in the European Union’s and applying the therapeutic and monitoring principles according to the same standards.
          The implementation of the project contributes to the increase of economic competitiveness between local economic operators, and in general it would have other positive consequences:

  • determining highly qualified personnel and young graduates to remain in the country;
  • changing the way Romanian research is perceived;
  • sustainable development by performing activities which do not deplete the environmental resources;
  • development of innovative and productive SMEs in the health sector;
  • reducing development gaps between different areas of the country, but especially between our  country and the EU. 

          Through this project of modernizing the R&D infrastructure of Colentina Clinical Hospital, it will be possible to carry out over 30 research project each year. The centres unique at national level: alergology, dermatovenerology, neurology and orthopedics will attract, in addition to partner/collaborator institutions, research physicians and research assistants for the occupation of the newly created jobs, numerous other persons who carry out activities in medical-surgical research specific fields.
          Having continuous regard to the pragmatic principles of the evidence-based medicine, the Colentina Research Centre will permanently develop original projects, with which it will take part in international project competitions. Due to the modern equipment of the centre, it will be possible to carry out functional and ultra structural studies by means of the non-invasive or minimum invasive environmental friendly technologies with low consumption of raw materials and energy, intended for sustainable development. The estimated results, will contribute to:

  • the increase of the medical scientific level at a national and international-European level;
  • he creation of a medical database with a view to establishing the common research directions and the application of its results in the current medical practice;
  • the creation of therapeutic guides resulting in the improvement of the patient quality of life by reducing the number of days in hospital, temporary unfitness for work, etc.;
  • the establishment of the medical surgical treatment types adapted to the etiopatogenesis in the inflammatory, infectious and tumour pathology;
  • the training and formation of personnel in the elite medical research in the field of inflammatory and tumour pathology;
  • the training of young specialist researchers in order for their scientific competitiveness to be comparable to that of their EU colleagues;
  • the introduction of certain complex diagnosis and treatment methods necessary for the accuracy of the diagnosis-therapeutic approach.

Project budget - the eligible value is 59,993,736 lei, approximately 17 millions euro.
The project’s duration is 24 months (2 years).